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Woman who had uterine cancer, turns mother; Chennai Doctors create history

Chennai Doctors perform the country’s first surrogate birth following egg extraction from an ovary transposition under the skin.

A woman (name not mentioned) had her uterus and the left ovary removed due to uterine cancer.

Five years later, the woman became a mother through surrogacy as fertility specialists, in a novel method, extracted the egg from the transposition ovary percutaneously, and fertilised it.

“Her uterus with fallopian tubes as well as the left ovary was removed in a hospital in Kerala. What was remaining was her right ovary. The only way she could have her child was through surrogacy. There was a twist as the right ovary along with its blood supply, instead of being lodged within the abdomen, was brought up through the abdominal wall and placed right beneath the skin,” she said.

Ovaries in cancer patients, she said, can be located within the abdomen or above the pelvic brim in case they had to go undergo radiation. In the literature search, the doctors found that people in this situation usually have their ovaries removed and later transplanted back once they are cancer free. In some cases, it moved out of its normal position in the pelvic area to just above the pelvis, and eggs are retrieved laparoscopically, she explained.

Being married and childless, the woman was referred to GG Hospital in August 2016. After detailed work-up, she was put on stimulant injections and doctors used a syringe (same as used in regular IVF procedures) to extract the eggs, but through the skin of the patient’s abdomen. The quality of eggs was another challenge, Dr Selvaraj added.

Three attempts later, doctors finally managed to get embryos out of such retrieval and implanted them a surrogate in 2018. She delivered a girl baby weighing 2.62 kg on February 16.

Doctors said this was the country’s first surrogate birth following egg extraction from an ovary transposition under the skin.

The hospital is now working to preserve ovarian tissue for future re-transplantation into the individual for fertility purpose after thawing. “Childhood cancers in pre/pubertal age group are maximum indicators for ovarian tissue preservation,” she added. Kamala Selvaraj, associate director of the hospital, was present.

As told to Hindu